Background:The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes.
仕様
Synonyms:Ah receptor,AhR,AHR,Aromatic hydrocarbon receptor,Aryl hydrocarbon receptor,Aryl hydrocarbon receptor precursor,bHLHe76,Class E basic helix loop helix protein 76,Class E basic helix-loop-helix protein 76,HGNC:348
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of human AHR
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:200 - 1:2000 IHC1:50 - 1:200
Gene_ID(human):196
Swissprot:P35869
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling