Background：This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：AA517111,Basement membrane protein 40,Basement-membrane protein 40,BM 40,BM-40,BM40,Cysteine rich protein,hm：zeh0062,MGC128090,OI17,ON,Osteonectin,Secreted acidic cystein rich glycoprotein,Secreted protein acidic and cysteine rich,Secreted protein acidic and rich in cysteine,Secreted protein acidic cysteine rich （osteonectin）,Secreted protein acidic cysteine rich,SPARC,SPRC,SPRC
Host：Rabbit
Reactivity：Human,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human SPARC
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：6678
Swissprot：P09486
Isotype：IgG
Research Areas：Cancer, Cell Biology, Cardiovascular, Developmental biology, Signal transduction, Stem cells
