Background:This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum.
仕様
Synonyms:Apotransferrin,Beta 1 metal binding globulin,Beta-1 metal-binding globulin,DKFZp781D0156,PRO1400,PRO1557,PRO2086,Serotransferrin,Serotransferrin precursor,Siderophilin,TF,TFQTL1,Transferin,Transferrin,TRFE
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human TF
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB 1:500 - 1:2000
Gene_ID(human):7018
Swissprot:P02787
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Metabolism, Signal transduction