Background：The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：3 hydroxy 3 methylglutaryl Coenzyme A synthase 2 （mitochondrial）,3 hydroxy 3 methylglutaryl Coenzyme A synthase 2,3 hydroxy 3 methylglutaryl coenzyme A synthase,3-hydroxy-3-methylglutaryl coenzyme A synthase,HMCS2,HMG CoA synthase,HMG-CoA synthase,HMGCS 2,HMGCS2,Hydroxymethylglutaryl CoA synthase,Hydroxymethylglutaryl CoA synthase mitochondrial,Hydroxymethylglutaryl-CoA synthase,mitochondrial
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human HMGCS2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：3158
Swissprot：P54868
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Metabolism, Signal transduction
