Background：The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene.
仕様
Synonyms：ACS2 ,ACS5 ,Acyl CoA synthetase 5,Acyl CoA synthetase long chain family member 5,EC 6.2.1.3,FACL5 ,FACL5 for fatty acid coenzyme A ligase 5,Fatty acid CoA ligase, long chain 5,Fatty acid coenzyme A ligase 5,Fatty acid Coenzyme A ligase long chain 5,LACS 5,Long chain acyl CoA synthetase 5,Long chain fatty acid CoA ligase 5 ,Long chain fatty acid coenzyme A ligase 5
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human ACSL5
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Dilution：WB1：500 - 1：2000
Gene_ID（human）：51703
Swissprot：Q9ULC5
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
