Background：This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex （DGC）, which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy （DMD）, Becker muscular dystrophy （BMD）, or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene.
仕様
Synonyms：BMD,CMD3B,DMD,DMD,Duchenne muscular dystrophy protein,Dystrophin,Muscular dystrophy Duchenne and Becker types
Host：Rabbit
Reactivity：Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human DMD
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB 1：200 - 1：2000
Gene_ID（human）：1756
Swissprot：P11532
Isotype：IgG
Research Areas：Cancer, Neuroscience, Signal transduction, Stem cells
