Background:This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation.
仕様
Synonyms:from Entrez Gene ;,HEC,Highly expressed in cancer,Highly expressed in cancer protein,Highly expressed in cancer rich in leucine heptad repeats,HsHec1,hsNDC80,Kinetochore associated 2,Kinetochore associated protein 2,Kinetochore protein Hec1,Kinetochore protein NDC80 homolog,Kinetochore-associated protein 2,KNTC2,ndc80,NDC80 homolog kinetochore complex component,NDC80 kinetochore complex component homolog,NDC80,S. cerevisiae,homolog of,NDC80,Retinoblastoma associated protein HEC,Retinoblastoma-associated protein HEC,TID3
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human NDC80
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Dilution:WB 1:500 - 1:2000
Gene_ID(human):10403
Swissprot:O14777
Isotype:IgG
Research Areas:Cancer, Cell Biology, Epigenetics and Nuclear Signaling