Background：This gene encodes a member of the HIN-200 （hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats） family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：IFI16,Gamma interferon inducible protein 16,Gamma-interferon-inducible protein Ifi16,IF16,Ifi204,IFNGIP1,interferon activated gene 204,Interferon gamma induced protein IFI 16,Interferon gamma inducible protein 16,Interferon-inducible myeloid differentiation transcriptional activator,p204,PYHIN2
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human IFI16
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：200
Gene_ID（human）：3428
Swissprot：Q16666
Isotype：IgG
Research Areas：Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism
