Background:In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome.
仕様
Synonyms:Homeo box 1J,Homeo box A13,Homeobox 1J,Homeobox A13,Homeobox protein Hox A13,Homeobox protein Hox-1J,Homeobox protein Hox-A13,Homeobox protein HOXA13,Homeobox1J,HomeoboxA13,HOX 1,HOX 1J,Hox 1J protein,HOX A13,HOX1,HOX1J,HOXA 13,HOXA13,HXA13,Transcription factor HOXA13
Host:Rabbit
Reactivity:Human
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human HOXA13
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):3209
Swissprot:P31271
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Developmental biology