Background：This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.
仕様
Synonyms：Aplysia ras related homolog 12,ARH12,ARHA,H 12,H12,Oncogene RHO H12,Ras homolog family member A,Ras homolog gene family member A,Rho A,Rho cDNA clone 12,RHO H12,RHO12,RHOA,RHOA,RHOH12,Small GTP binding protein Rho A,Transforming protein Rho A,Transforming protein RhoA
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC
Concentration：1mg/ml
Immunogen：A synthetic peptide of human RhoA
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
