Background：This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
仕様
Synonyms：AQP 4,AQP-4,AQP4,AQP4,Aquaporin type 4,Aquaporin-4,Aquaporin4,HMIWC 2,HMIWC2,Mercurial insensitive water channel,Mercurial-insensitive water channel,MGC22454,MIWC,WCH 4,WCH4
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human AQP4
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：IHC1：50 - 1：200
Gene_ID（human）：361
Swissprot：P55087
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
