Background:This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease.
仕様
Synonyms:Alpha glucosidase II alpha subunit,Alpha-glucosidase 2,G2AN,GANAB,GANAB,Glu II,Glucosidase alpha neutral AB,Glucosidase II alpha,Glucosidase II subunit alpha,GluII,KIAA0088,Neutral alpha glucosidase AB,Neutral alpha glucosidase AB precursor,Neutral alpha-glucosidase AB
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human GANAB
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):23193
Swissprot:Q14697
Isotype:IgG
Research Areas:Cancer, Metabolism, Signal transduction