Background：This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.
仕様
Synonyms：I MF,I mfa,Inhibitor of MyoD family a,Mdfi,MDFI,MyoD family inhibitor,Myogenic repressor I-mf,OTTHUMP00000016375,OTTHUMP00000016376,OTTHUMP00000196103,OTTHUMP00000196414,OTTHUMP00000196415
Host：Rabbit
Reactivity：Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human MDFI
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：4188
Swissprot：Q99750
Isotype：IgG
Research Areas：Epigenetics and Nuclear Signaling, Developmental biology
