Background：Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components： P protein （a pyridoxal phosphate-dependent glycine decarboxylase）, H protein （a lipoic acid-containing protein）, T protein （a tetrahydrofolate-requiring enzyme）, and L protein （a lipoamide dehydrogenase）. The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia （NKH）. Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.
仕様
Synonyms：GCE,GCSH,GCSH,Glycine cleavage system H protein,Glycine cleavage system H protein mitochondrial,Glycine cleavage system protein H （aminomethyl carrier）,Glycine cleavage system protein H,Lipoic acid containing protein,mitochondrial,Mitochondrial glycine cleavage system H protein,NKH
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human GCSH
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：2653
Swissprot：P23434
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction, Tags ＆ Cell Markers
