Background:The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
仕様
Synonyms:MGC40331,Retinoic acid induced gene B protein,Retinoic acid-induced gene B protein,RIG B,RIG-B,UB2L6,UBCH 8,UbcH8,UBE2L6,Ubiquitin carrier protein,Ubiquitin carrier protein L6,Ubiquitin conjugating enzyme E2L 6,Ubiquitin protein ligase,Ubiquitin protein ligase L6,Ubiquitin-protein ligase L6,Ubiquitin/ISG15 conjugating enzyme E2 L6,Ubiquitin/ISG15-conjugating enzyme E2 L6
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:A synthetic peptide of human UBE2L6
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):9246
Swissprot:O14933
Isotype:IgG
Research Areas:Cell Biology, Epigenetics and Nuclear Signaling