Background：This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor （TNF）. The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene.
仕様
Synonyms：A20,AISBL,MGC104522,MGC138687,MGC138688,OTU domain containing protein 7C,OTU domain-containing protein 7C,OTUD7C,Putative DNA binding protein A20,Putative DNA-binding protein A20,TNAP3,TNF alpha-induced protein 3,TNFA1P2,TNFAIP 3,TNFAIP3 （A20）,TNFAIP3,Tumor necrosis factor alpha induced protein 3,Tumor necrosis factor alpha-induced protein 3,Tumor necrosis factor induced protein 3,Tumor necrosis factor inducible protein A20,tumor necrosis factor,alpha-induced protein 3,Zinc finger protein A20
Host：Rabbit
Reactivity：Human,Rat
Applications：IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human TNFAIP3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：IF1：50 - 1：200
Gene_ID（human）：7128
Swissprot：P21580
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Immunology, Signal transduction
