Background：The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor （PDGF/VEGF） family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C. Read-through transcription has been observed between this locus and the upstream PIR （GeneID 8544） locus.
