Background：The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：BNSP,Bone sialoprotein 1,BSP I,BSPI,Early T lymphocyte activation 1,ETA 1,ETA1,MGC110940,Nephropontin,OPN,Osteopontin,osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein,OSTP,PSEC0156,secreted phosphoprotein 1 （osteopontin,bone sialoprotein I,early T-lymphocyte activation 1）,Secreted phosphoprotein 1,SPP 1,SPP-1,SPP1,SPP1/CALPHA1 fusion,Urinary stone protein,Uropontin
Host：Rabbit
Reactivity：Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human SPP1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：6696
Swissprot：P10451
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Signal transduction, Stem cells
