Background：This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor （TIR） homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors （TLRs） and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response.
仕様
Synonyms：IIAE6,MGC35334,MyD88 3,Proline rich vinculin and TIR domain containing protein B,Proline-rich,PRVTIRB,Putative NF kappa B activating protein 502H,Putative NF-kappa-B-activating protein 502H,Putative NFkB activating protein,TCAM1,TICAM 1,TICAM-1,Ticam1,TIR domain containing adapter molecule 1,TIR domain containing adapter protein inducing IFN beta,TIR domain containing adaptor inducing interferon beta,TIR domain-containing adapter molecule 1,TIR domain-containing adapter protein inducing IFN-beta,Toll interleukin 1 receptor domain containing adapter protein inducing interferon beta,Toll like receptor adaptor molecule 1,Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta,TRIF,TRIF protein,vinculin and TIR domain-containing protein B
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human TICAM1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
