Background:This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been defined on chromosome 21.
仕様
Synonyms:bHLHb11,Class B basic helix-loop-helix protein 11,FCHL 1,FCHL,FCHL1,HGNC:12593,HYPLIP 1,HYPLIP1,Major late transcription factor 1,Major late transcription factor,MLTF,MLTF I,MLTFI,Transcription factor USF-1,UEF,Upstream stimulatory factor 1,Upstream transcription factor 1,Upstream transcription factor 1,isoform CRA_a,USF 1,USF
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of human USF1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Dilution:WB1:500 - 1:2000 IHC1:50 - 1:200
Gene_ID(human):7391
Swissprot:P22415
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism