Background：This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized.
仕様
Synonyms：D11Wsu78e,DNA ligase,DNA ligase 3,DNA ligase III,DNLI3,LIG 3,LIG2,LIG3,Ligase II,DNA,ATP dependent,Ligase III DNA ATP dependent,MGC78176,OTTMUSP00000000875,Polydeoxyribonucleotide synthase [ATP] 3,Polydeoxyribonucleotide synthase [ATP],Polydeoxyribonucleotide synthase,RP23-316C11.6
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human LIG3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：200
Gene_ID（human）：3980
Swissprot：P49916
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
