Background：In mammals, histamine is metabolized by two major pathways： N（tau）-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N（tau）-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.
仕様
Synonyms：EC 2.1.1.8,Histamine N methyltransferase,Histamine N-methyltransferase,HMT,HNMT,HNMT S1,HNMT S2,HNMT
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC,IP
Concentration：1mg/ml
Immunogen：Recombinant protein of human HNMT
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
