Background：This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
仕様
Synonyms：DDIT 1,DDIT-1,DDIT1,DNA damage inducible transcript 1,DNA damage-inducible transcript 1 protein,GA45A,GADD45,GADD45A,Growth arrest and DNA damage inducible 45 alpha ,Growth arrest and DNA damage inducible alpha,Growth arrest and DNA damage-inducible protein GADD45 alpha
Host：Rabbit
Reactivity：Human,Mouse
Applications：IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human GADD45A
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：IF1：50 - 1：200
Gene_ID（human）：1647
Swissprot：P24522
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
