Background：This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：CP51,CP51A,CYP51,CYP51A1,CYPL1,CYPLI,Cytochrome P450 51,Cytochrome P450 51A1,Cytochrome P450 family 51 subfamily A member 1,Cytochrome P450 family 51 subfamily A polypeptide 1,Cytochrome P450, 51 （lanosterol 14 alpha demethylase）,Cytochrome P450-14DM,Cytochrome P45014DM,Cytochrome P450LI,Lanosterol 14-alpha demethylase,LDM,P450 14DM,P450L1,Sterol 14-alpha demethylase
Host：Rabbit
Reactivity：Human,Mouse
Applications：IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human CYP51A1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：IF1：50 - 1：200
Gene_ID（human）：1595
Swissprot：Q16850
Isotype：IgG
Research Areas：Cardiovascular, Metabolism, Signal transduction
