Background：The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. In addition, the mature peptide has antimicrobial activity against some bacteria and fungi, including S. pneumoniae and C. albicans. Alternative splicing results in two transcript variants encoding the same protein. This gene and the gene that encodes ribonuclease, RNase A family, 4 share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region.
仕様
Synonyms：ALS9,AMYOTROPHIC LATERAL SCLEROSIS,ANG 1,ANG,ANG I,ANG1,ANGI,ANGI,Angiogenin,Angiogenin ribonuclease RNase A family,5,Epididymis luminal protein 168,HEL168,MGC22466,MGC71966,Ribonuclease 5,Ribonuclease RNase A Family 5,RNase 5,RNASE4,RNASE5
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human ANG
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：283
Swissprot：P03950
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Signal transduction
