Background:The protein encoded by this gene is a member of the LIM homeobox family of proteins, which are involved in patterning and differentiation of various tissue types. These proteins contain two tandemly repeated cysteine-rich double-zinc finger motifs known as LIM domains, in addition to a DNA-binding homeodomain. This family member is a transcription factor that plays a role in tooth morphogenesis. It is also involved in oogenesis and in neuronal differentiation. This gene is a candidate gene for cleft palate, and it is also associated with odontoma formation. Alternative splicing of this gene results in multiple transcript variants.
仕様
Synonyms:Lhx7,Lhx8,LHX8,LIM Homeobox 8,LIM homeobox protein 8,LIM Homeodomain 8,LIM/homeobox protein Lhx8
Host:Rabbit
Reactivity:Human
Applications:IF
Concentration:1mg/ml
Immunogen:Recombinant protein of human LHX8
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:IF1:50 - 1:200
Gene_ID(human):431707
Swissprot:Q68G74
Isotype:IgG
Research Areas:Epigenetics and Nuclear Signaling, Developmental biology, Stem cells