Background：The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 （Th1） and 2 （Th2） on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
仕様
Synonyms：CD366,FLJ14428,HAVcr-2,Havcr2,HAVR2,Hepatitis A virus cellular receptor 2,Kidney injury molecule 3,KIM 3,KIM3,T cell immunoglobulin and mucin domain containing 3,T cell immunoglobulin mucin 3,T-cell immunoglobulin and mucin domain-containing protein 3,T-cell immunoglobulin mucin family member 3,T-cell immunoglobulin mucin receptor 3,T-cell membrane protein 3,Tim 3,TIM-3,TIM3,TIMD-3,TIMD3
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human HAVCR2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
