Background：The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：OTTHUMP00000020374,OTTHUMP00000020377,OTTHUMP00000020379,PRO1280,SU FU,SU（F）U,Su（fu）,SUFU,SUFU negative regulator of hedgehog signaling,SUFU,SUFUH,SUFUXL,Suppressor of fused homolog （Drosophila）,Suppressor of fused homolog
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human SUFU
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IF1：50 - 1：200
Gene_ID（human）：51684
Swissprot：Q9UMX1
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
