Background:This gene encodes a protein with multiple WD40 repeats which facilitate protein-protein interactions and thereby enable the assembly of multiprotein complexes. This protein has been shown to function as a scaffold protein for protein complexes involved in kinase signaling. This highly conserved gene is present in eukaryotic plants, fungi, and animals. The ortholog of this gene was first identified in plants as a key regulator of anthocyanin biosynthesis and flower pigmentation. Alternative splicing results in multiple transcript variants.
仕様
Synonyms:AN11,Dcaf7,DCAF7,DDB1- and CUL4-associated factor 7,HAN11 ,Human anthocyanin,Petunia,Seven WD repeat protein of the AN11 family 1,SWAN 1,WD repeat domain 68,WD repeat protein An11 homolog ,WD repeat-containing protein 68,WD repeat-containing protein An11 homolog,WDR68
Host:Rabbit
Reactivity:Human,Mouse
Applications:IF
Concentration:1mg/ml
Immunogen:Recombinant protein of human DCAF7
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:IF1:50 - 1:200
Gene_ID(human):10238
Swissprot:P61962
Isotype:IgG
Research Areas:Cancer, Cell Biology, Signal transduction