Background：Ubiquitin is a highly conserved protein that is covalently linked to other proteins to regulate their function and degradation. This gene encodes a member of the ubiquitin-specific protease family of cysteine proteases. The enzyme specifically cleaves ubiquitin from ubiquitin-conjugated protein substrates. The protein is found in the nucleus and cytoplasm. It functions as a co-factor of the DNA-bound androgen receptor complex, and is inhibited by a protein in the Ras-GTPase pathway. The human genome contains several pseudogenes similar to this gene. Several transcript variants, some protein-coding and others not protein-coding, have been found for this gene.
仕様
Synonyms：Deubiquitinating enzyme 10,KIAA0190,MGC124997,MGC2621,Ubiquitin carboxyl terminal hydrolase 10,Ubiquitin carboxyl-terminal hydrolase 10,Ubiquitin specific peptidase 10,Ubiquitin specific processing protease 10,Ubiquitin specific protease 10,Ubiquitin thioesterase 10,Ubiquitin thiolesterase 10,Ubiquitin-specific-processing protease 10,UBP10,UBPO,USP 10,USP10
Host：Rabbit
Reactivity：Human,Mouse
Applications：IHC,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human USP10
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：IHC1：50 - 1：200 IF1：50 - 1：200
Gene_ID（human）：9100
Swissprot：Q14694
Isotype：IgG
Research Areas：Cancer, Cell Biology, Epigenetics and Nuclear Signaling
