Background：Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain （6 carbons or more） saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified.
仕様
Synonyms：Acetaldehyde dehydrogenase 3,AHD 4,AHD C,AHD4,AHDC,AL3A1,Aldehyde dehydrogenase 3,Aldehyde dehydrogenase 3 family member A1,Aldehyde dehydrogenase 3A1,Aldehyde dehydrogenase,Aldehyde dehydrogenase class 3,Aldehyde dehydrogenase dimeric NADP preferring,Aldehyde dehydrogenase family 3 member A1,Aldehyde dehydrogenase family 3 subfamily A1,Aldehyde dehydrogenase family 3,subfamily A,member 1,Aldehyde dehydrogenase isozyme 3,Aldehyde dehydrogenase type III,ALDH 3,ALDH 3A1,ALDH III,ALDH,stomach type,ALDH3 A1,ALDH3,ALDH3A 1,Aldh3a1,ALDHIII,dimeric NADP-preferring,MGC10406,Stomach aldehyde dehydrogenase,Tumor associated aldehyde dehydrogenase tumor ALDH
