Background：The protein encoded by this gene localizes to the endoplasmic reticulum, where it catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester. This reaction is an important step in vitamin A metabolism in the visual system. Mutations in this gene have been associated with early-onset severe retinal dystrophy and Leber congenital amaurosis 14. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：LCA14,Lecithin retinol acyltransferase （phosphatidylcholine retinol O acyltransferase）,Lecithin retinol acyltransferase,LRAT,LRAT,Phosphatidylcholine retinol O acyltransferase,Phosphatidylcholine--retinol O-acyltransferase
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human LRAT
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB 1：1000 - 1：2000
Gene_ID（human）：9227
Swissprot：O95237
Isotype：IgG
Research Areas：Cancer, Metabolism, Neuroscience, Signal transduction
