Background：The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3.
仕様
Synonyms：A esterase 1,A-esterase 1,Aromatic esterase 1,Arylesterase 1,Arylesterase B type,ESA,Esterase A,K 45,K-45,MVCD5,Paraoxonase 1,Paraoxonase,Paraoxonase B type,Paraoxonase,plasma,Paraoxonase1,PON 1,PON,PON1,PON1,Serum aryldiakylphosphatase,Serum aryldialkylphosphatase 1,Serum paraoxonase/arylesterase 1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human PON1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：5444
Swissprot：P27169
Isotype：IgG
Research Areas：Cancer, Cell Biology, Cardiovascular, Metabolism, Neuroscience, Signal transduction
