Background:This gene is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.
仕様
Synonyms:Equilibrative NBMPR-sensitive nucleoside transporter,equilibrative nitrobenzylmercaptopurine riboside (NBMPR)-sensitive nucleoside transporter,Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter,Equilibrative nucleoside transporter 1,es-type,MGC1465,MGC3778,Nucleoside transporter,Nucleoside transporter,es-type,OTTHUMP00000016506,OTTHUMP00000016507,OTTHUMP00000016508,OTTHUMP00000016509,OTTHUMP00000016510,OTTHUMP00000016511,OTTHUMP00000016512,S29A1,Slc29a1,solute carrier family 29 (equilibrative nucleoside transporter),member 1,solute carrier family 29 (nucleoside transporters),member 1,Solute carrier family 29 member 1
Host:Rabbit
Reactivity:Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:A synthetic peptide of human SLC29A1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):2030
Swissprot:Q99808
Isotype:IgG
Research Areas:Cancer, Metabolism, Signal transduction