Background：This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：and NACHT-containing protein,CARD 12,CARD,CARD LRR and NACHT containing protein 1,CARD LRR and NACHT containing protein,CARD12,Caspase recruitment domain containing protein 12,Caspase recruitment domain family member 12,Caspase recruitment domain-containing protein 12,CLAN 1,CLAN A,CLAN,CLAN B,CLAN C,CLAN D,Clan protein,CLAN1,CLANA,CLANB,CLANC,CLAND,CLR 2.1,CLR2.1,ICE protease activating factor,Ice protease-activating factor,Ipaf,LRR,NLR family CARD domain containing 4,NLR family CARD domain-containing protein 4,NLRC 4,NLRC4,NLRC4,NOD like receptor C4,Nucleotide binding oligomerization domain leucine rich repeat and CARD domain containing 4,UNQ6189/PRO20215
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant Protein of mouse NLRC4
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：268973
Swissprot：Q3UP24
Isotype：IgG
Research Areas：Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism, Immunology
