Background：The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin （beta2M）. It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.
仕様
Synonyms：dJ221C16.10.1,Hemochromatosis,Hemochromatosis protein,Hereditary hemochromatosis protein,Hereditary hemochromatosis protein HLA H,HFE 1,HFE,HFE,HFE1,HH,High Fe,HLA H,HLA-H,HLAH,MGC：150812,MGC10379,MGC103790,MHC class I like protein HFE,MVCD7,TFQTL2
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human HFE
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IF1：50 - 1：200
Gene_ID（human）：3077
Swissprot：Q30201
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction, Stem cells
