Background：The protein encoded by this gene is a member of the membrane-associated guanylate kinase-like （MAGUK） protein family which is characterized by members having multiple PDZ domains, a single SH3 domain, and a single guanylate kinase-like （GUK）-domain. In addition, members of the zonula occludens protein subfamily have an acidic domain, a basic arginine-rich region, and a proline-rich domain. The protein encoded by this gene plays a role in the linkage between the actin cytoskeleton and tight-junctions and also sequesters cyclin D1 at tight junctions during mitosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. This gene has a partial pseudogene on chromosome 1.
仕様
Synonyms：Tight junction protein 3,Tight junction protein ZO-3,Tight junction protein ZO3,TJP3,ZO3,ZO3,Zona occludens protein 3,Zonula occludens protein 3
Host：Rabbit
Reactivity：Human
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant Protein of human TJP3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
