Background:The protein encoded by this gene is a peroxisomal thioesterase that appears to be involved more in the oxidation of fatty acids rather than in their formation. The encoded protein can bind to the human immunodeficiency virus-1 protein Nef, and mediate Nef-induced down-regulation of CD4 in T-cells.
仕様
Synonyms:ACTEIII,Acot8,ACOT8,Acyl CoA thioesterase 8,Acyl-CoA thioesterase 8,Acyl-coenzyme A thioesterase 8,Choloyl coenzyme A thioesterase,Choloyl-coenzyme A thioesterase,hACTE III,hACTE-III,hACTEIII,HIV Nef associated acyl CoA thioesterase,HIV-Nef-associated acyl-CoA thioesterase,HNAACTE,hTE,Long chain fatty acyl CoA hydrolase,Palmitoyl CoA hydrolase,Peroxisomal acyl CoA thioesterase 1,Peroxisomal acyl coenzyme A thioester hydrolase 1,Peroxisomal acyl-coenzyme A thioester hydrolase 1,Peroxisomal long chain acyl CoA thioesterase 1,Peroxisomal long-chain acyl-CoA thioesterase 1,PTE 1,PTE 2,PTE-1,PTE-2,PTE1,PTE2,Thioesterase II
Host:Rabbit
Reactivity:Human
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant Protein of human ACOT8
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):10005
Swissprot:O14734
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Metabolism, Immunology, Signal transduction