Background：This gene encodes a mosaic protein that belongs to at least two families： the vacuolar protein sorting 10 （VPS10） domain-containing receptor family, and the low density lipoprotein receptor （LDLR） family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded preproprotein is proteolytically processed to generate the mature receptor, which likely plays roles in endocytosis and sorting. Mutations in this gene may be associated with Alzheimer's disease.
仕様
Synonyms：C11orf32,FLJ21930,FLJ39258,gp250,LDLR relative with 11 ligand binding repeats,LDLR relative with 11 ligand-binding repeats,Low density lipoprotein receptor relative with 11 ligand binding repeats,Low-density lipoprotein receptor relative with 11 ligand-binding repeats,LR 11,LR11,LRP 9,LRP9,Mosaic protein LR11,SORL 1,SORL,SORL1,SorLA 1,SorLA,SorLA-1,Sortilin related receptor,Sortilin related receptor L（DLR class） A repeats containing,Sortilin-related receptor,Sorting protein related receptor containing LDLR class A repeats,Sorting protein-related receptor containing LDLR class A repeats
Host：Rabbit
Reactivity：Human
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant Protein of human SORL1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：6653
Swissprot：Q92673
Isotype：IgG
Research Areas：Cancer, Neuroscience, Signal transduction
