Background：This gene encodes a subunit of mitochondrial NADH：ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome.
仕様
Synonyms：CI 23kD,CI-23kD,Complex I 23kD,Complex I-23kD,EC 1.6.5.3,EC 1.6.99.3,Human mitochondrial NADH dehydrogenase ubiquinone Fe S protein 8,NADH dehydrogenase [ubiquinone] iron-sulfur protein 8,mitochondrial,NADH ubiquinone oxidoreductase 23 kDa subunit,NADH-ubiquinone oxidoreductase 23 kDa subunit,NDUFS8,NDUS8,TYKY,TYKY subunit,Ubiquinoneiron sulfur protein 8,mitochondrial precursor
Host：Rabbit
Reactivity：Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant Protein of human NDUFS8
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：4728
Swissprot：O00217
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction, Tags ＆ Cell Markers
