Background:The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome.
仕様
Synonyms:CD 40L,CD154,CD40 antigen ligand,CD40 ligand,CD40 ligand,soluble form,CD40-L,CD40L,CD40L,CD40LG,gp39,hCD40L,HIGM1,IGM,IMD3,T B cell activating molecule,T BAM,T-cell antigen Gp39,TNF-related activation protein,TNFSF5,TrAP,Tumor necrosis factor (ligand) superfamily member 5,Tumor necrosis factor ligand superfamily member 5