Background:This gene encodes a member of the EH domain-containing protein family. These proteins are characterized by a C-terminal EF-hand domain, a nucleotide-binding consensus site at the N terminus and a bipartite nuclear localization signal. The encoded protein interacts with the actin cytoskeleton through an N-terminal domain and also binds to an EH domain-binding protein through the C-terminal EH domain. This interaction appears to connect clathrin-dependent endocytosis to actin, suggesting that this gene product participates in the endocytic pathway.
仕様
Synonyms:EH domain containing 2,EH domain containing 3,EH domain containing protein 2,EH domain-containing protein 2,EHD 2,Ehd2,EHD2,EHD3,FLJ96617,PAST 2,PAST homolog 2,PAST2
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human EHD2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:1000 - 1:3000
Gene_ID(human):30846
Swissprot:Q9NZN4
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling