Background：This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A （CoA） hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.
仕様
Synonyms：4）-dienoyl-CoA isomerase,5）-Delta（2,Delta（3 5） Delta（2 4） dienoyl CoA isomerase,Delta（3 5） Delta（2 4） dienoyl CoA isomerase mitochondrial,Delta（3,Delta3 5 delta2 4 dienoyl CoA isomerase,Dienoyl CoA isomerase,ECH 1,Ech1,ECH1,Enoyl Coenzyme A hydratase 1,Enoyl Coenzyme A hydratase 1 peroxisomal,HPXEL,mitochondrial,MS1034,Peroxisomal enoyl CoA hydratase 1,Peroxisomal enoyl coenzyme A hydratase like protein
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human ECH1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Dilution：WB1：500 - 1：2000
Gene_ID（human）：1891
Swissprot：Q13011
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Metabolism, Signal transduction, Tags ＆ Cell Markers
