Background:The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.
仕様
Synonyms:Claudin-4,Claudin4,CLD4,CLDN 4,CLDN4,Clostridium perfringens enterotoxin receptor 1,Clostridium perfringens enterotoxin receptor,CPE R,CPE receptor,CPE-R,CPE-receptor,CPER,CPETR 1,CPETR,CPETR1,hCPE R,WBSCR8,Williams Beuren syndrome chromosome region 8 protein,Williams-Beuren syndrome chromosomal region 8 protein
Host:Rabbit
Reactivity:Human
Applications:WB
Concentration:1mg/ml
Immunogen:A synthetic peptide of human CLDN4
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.