Background：This gene encodes a RPIP8, UNC-14, and NESCA domain-containing protein that is required for maintenance of neuronal polarity. In addition, it has been implicated in mediation of gastric cancer cell migration and invasion via interaction with P21-activated kinase-1, which promotes its expression. The encoded protein localizes to F-actin-enriched invadopodia to induce formation of protrusions, thereby facilitating cell migration. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：Protein RUFY3,rap2 interacting protein x,Rap2 interacting protein x isoform 2,Rap2-interacting protein x,RIPx,Rpipx,Rufy3,RUFY3,RUN and FYVE domain containing 3,Singar,Singar1,Single axon regulated protein,single axon related 1,Single axon-regulated protein
Host：Rabbit
Reactivity：Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human RUFY3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
