Background：This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：CDC2L1,CDK11,Cell division cycle 2-like protein kinase 1,Cell division protein kinase 11B,CLK 1,EC=2.7.11.22,Galactosyltransferase associated protein kinase p58/GTA,ITSLRE serine/threonine protein kinase CDC2L1,p58 CLK 1,PITSLREA,PK58
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human CDK11B
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Dilution：WB1：500 - 1：2000
Gene_ID（human）：984
Swissprot：P21127
Isotype：IgG
Research Areas：Cancer, Cell Biology, Epigenetics and Nuclear Signaling
