Background：This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin （SNX） family and the regulator of G protein signaling （RGS） family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha（s）, accelerates its GTP hydrolysis, and attenuates G alpha（s）-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking.
仕様
Synonyms：KIAA0713,RGS domain and PHOX domain containing protein,RGS PX1,Sorting nexin 13
Host：Rabbit
Reactivity：Human
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human SNX13
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
