Background:This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene.
仕様
Synonyms:eed,EED protein,EED, mouse, homolog of,EED,Embryonic ectoderm development,Embryonic ectoderm development isoform a,Embryonic ECTODERM development protein homolog ,Embryonic ectoderm development protein, mouse, homolog of,hEED,OTTHUMP00000235483,OTTHUMP00000235484,OTTHUMP00000235485,Polycomb protein eed,WAIT 1,WAIT-1,WAIT1,WD protein associating with integrin cytoplasmic tails 1
Host:Rabbit
Reactivity:Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:A synthetic peptide of human EED
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Dilution:WB1:500 - 1:2000
Gene_ID(human):8726
Swissprot:O75530
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling