Background：This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair （BER） pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms： the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene （GeneID 10309）, which has been confused with this gene, in the literature and some databases.
仕様
Synonyms：DGU,DKFZp781L1143,HIGM 4,HIGM4,OTTHUMP00000240527,OTTHUMP00000240528,OTTHUMP00000240529,UDG,UNG 1,UNG 15,ung,UNG,UNG1,UNG15,UNG2,Uracil DNA glycosylase 1,Uracil DNA glycosylase 2,Uracil DNA glycosylase,Uracil-DNA glycosylase
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human UNG
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：1000 - 1：2000 IHC1：50 - 1：100
Gene_ID（human）：7374
Swissprot：P13051
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
