Background:This gene encodes a component of the chromosomal passenger complex. This complex is an essential regulator of mitosis and cell division. This protein is cell-cycle regulated and is required for chromatin-induced microtubule stabilization and spindle formation. Alternate splicing results in multiple transcript variants. Pseudgenes of this gene are found on chromosomes 7, 8 and 16.
仕様
Synonyms:BOR,BOREA,Borealin,CDCA8,Cell division cycle associated 8,cell division cycle associated protein 8,Cell division cycle-associated protein 8,Dasra B,Dasra-B,DasraB,FLJ10468,FLJ12042,hDasra B,hDasra-B,MESRGP,OTTHUMP00000004514,pluripotent embryonic stem cell related gene 3 protein,Pluripotent embryonic stem cell-related gene 3 protein
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of human CDCA8
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:1000 IHC1:50 - 1:100
Gene_ID(human):55143
Swissprot:Q53HL2
Isotype:IgG
Research Areas:Cell Biology, Epigenetics and Nuclear Signaling